Advanced Ultrasound in Diagnosis and Therapy ›› 2023, Vol. 7 ›› Issue (4): 405-408.doi: 10.37015/AUDT.2023.220049
• Case Reports • Previous Articles Next Articles
Lanxia Zhang, MMa, Qingjing Zeng, MDa, Guanghui Guo, MMa, Xuqi He, MMa, Kai Li, MDa,*()
Received:
2022-12-22
Revised:
2023-03-09
Accepted:
2023-05-09
Online:
2023-12-30
Published:
2023-10-23
Contact:
Kai Li, MD,
E-mail:likai@mail.sysu.edu.cn
Lanxia Zhang, MM, Qingjing Zeng, MD, Guanghui Guo, MM, Xuqi He, MM, Kai Li, MD. An Epstein-Barr Virus Positive Lymphoepithelioma-Like Cholangiocarcinoma in A Young Woman with Chronic Hepatitis B Treated through Microwave Ablation: A Case Report and Literature Review. Advanced Ultrasound in Diagnosis and Therapy, 2023, 7(4): 405-408.
Figure 1
A space-occupying lesion of 12 × 8 mm was found in the segment VI of liver. (A) Grayscale ultrasound findings: hypoechoic lesion with no obvious blood flow signals; contrast-enhanced ultrasonography findings: (B) Hyperenhancement in the arterial phase; (C) Hypoenhancement in both the portal phase and delayed phase (D). Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid-enhanced magnetic resonance findings: (E) Hypointensity in T1-weighted image; (F) Hyperintensity in T2-weighted image; (G) Hyperenhancement in the arterial phase; (H) Hypoenhancement in the portal phase."
Figure 2
A residual tumor was found 8 months after RFA. Contrast-enhanced ultrasonography findings: (A) Hyperenhancement in the arterial phase; (B) Hypoenhancement in the delayed phase. Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid-enhanced magnetic resonance findings: (C) Hyperenhancement in the arterial phase."
Table 1
Summary of the ultrasonic features of lymphoepithelioma-like cholangiocarcinoma reported in the english literatures"
Reference | Age | Sex | EBV | HBV | HCV | Size (cm) | Ultrasound | CEUS | |
---|---|---|---|---|---|---|---|---|---|
1 | Our | 28 | F | P | P | N | 1.2 | Hypoechoic lesion with no obvious blood flow signals | Hyperenhancement in the arterial phase, hypoenhancement in the portal phase and delayed phase |
2 | Chen et al. [14] | 67 | F | P | N | P | 5 | Mixed echoic | Unknown |
3 | Chen et al. [14] | 41 | M | N | P | N | 3 | Hypoechoic | Unknown |
4 | Jeng et al. [15] | 50 | F | P | P | N | 4 | Hypoechoic | Unknown |
5 | Liao et al. [2] | 35 | F | P | P | N | 1.7 | Hypoechoic | Unknown |
6 | Liang et al. [16] | 64 | M | P | P | N | 2.3 | Hypoechoic nodule with no blood flow signals | Unknown |
7 | Liang et al. [16] | 40 | M | P | P | N | 3.5 | Hypoechoic nodule with no blood flow signals | Hyperenhancement in the arterial phase, hypoenhancement and rim-like slight hyperenhancement in the portal phase and delayed phase |
8 | Nogami et al. [5] | 27 | F | P | P | N | 1 | Hypoechoic | Hyperenhancement in the arterial phase, perfusion defect in the Kupffer phase |
9 | Zhang et al. [17] | 36 | F | P | N | N | 11.5 | Hypoechoic | Unknown |
10 | Li et al. [6] | 51 | M | N | N | P | 5.1 | Hypoechoic | Hyperenhancement in the arterial phase, hypoenhancement in the portal and delay phases |
11 | Chen et al. [18] | 74 | F | P | N | N | 4.3 | Hypoechoic and aberrant subcapsular vascular patterns | Enhancement in the arterial phase, hypoenhancement in the portal and delay phases |
[1] |
Huang YH, Zhang CZ, Huang QS, Yeong J, Wang F, Yang X, et al. Clinicopathologic features, tumor immune microenvironment and genomic landscape of Epstein-Barr virus-associated intrahepatic cholangiocarcinoma. J Hepatol 2021; 74:838-849.
doi: 10.1016/j.jhep.2020.10.037 |
[2] |
Liao TC, Liu CA, Chiu NC, Yeh YC, Chiou YY. Lymphoepithelioma-like cholangiocarcinoma: A mimic of hepatocellular carcinoma on imaging features. World J Gastroenterol 2015; 21:4089-4095.
doi: 10.3748/wjg.v21.i13.4089 |
[3] |
Labgaa I, Stueck A, Ward SC. Lymphoepithelioma-like carcinoma in liver. Am J Pathol 2017; 187:1438-1444.
doi: S0002-9440(17)30177-3 pmid: 28500863 |
[4] |
Chiang NJ, Hou YC, Tan KT, Tsai HW, Lin YJ, Yeh YC, et al. The immune microenvironment features and response to immunotherapy in EBV-associated lymphoepithelioma-like cholangiocarcinoma. Hepatol Int 2022; 16:1137-1149.
doi: 10.1007/s12072-022-10346-3 |
[5] |
Nogami A, Saito S, Hasegawa H, Yoneda M, Harada K, Fujikawa H. Lymphoepithelioma-like cholangiocarcinoma with Epstein-Barr virus infection treated by radiofrequency ablation. Clin J Gastroenterol 2021; 14:638-644.
doi: 10.1007/s12328-020-01303-4 pmid: 33400192 |
[6] | Li X, Ji H, Zhang D, Jin M, Guo X, Gao P, et al. Lymphoepithelioma-like cholangiocarcinoma with hepatitis C virus infection treated by microwave ablation: A literature review and case report. Cancer Manag Res 2022; 14:2155-2160. |
[7] |
Vortmeyer AO, Kingma DW, Fenton RG, Curti BD, Jaffe ES, Duray PH. Hepatobiliary lymphoepithelioma-like carcinoma associated with Epstein-Barr virus. Am J Clin Pathol 1998; 109:90-95.
doi: 10.1093/ajcp/109.1.90 pmid: 9426523 |
[8] |
Yang Q, Cai Q, Wen H, Mao Y, Ban X, Rong D, et al. The CT and MRI features of primary intrahepatic lymphoepithelioma-like cholangiocarcinoma. AJR Am J Roentgenol 2021; 216:393-402.
doi: 10.2214/AJR.20.22937 |
[9] |
Wang XL, Li K, Su ZZ, Huang ZP, Wang P, Zheng RQ. Assessment of radiofrequency ablation margin by MRI-MRI image fusion in hepatocellular carcinoma. World J Gastroenterol 2015; 21:5345-5351.
doi: 10.3748/wjg.v21.i17.5345 |
[10] |
Li C, Zhu A. Application of image fusion in diagnosis and treatment of liver cancer. Applied Sciences 2020; 10:1171.
doi: 10.3390/app10031171 |
[11] |
Facciorusso A, Abd El Aziz MA, Tartaglia N, Ramai D, Mohan BP, Cotsoglou C, et al. Microwave ablation versus radiofrequency ablation for treatment of hepatocellular carcinoma: a meta-analysis of randomized controlled trials. Cancers (Basel) 2020; 12:3796.
doi: 10.3390/cancers12123796 |
[12] |
Zhang M, Ma H, Zhang J, He L, Ye X, Li X. Comparison of microwave ablation and hepatic resection for hepatocellular carcinoma: a meta-analysis. Onco Targets Ther 2017; 10:4829-4839.
doi: 10.2147/OTT |
[13] |
Li FY, Li JG, Wu SS, Ye HL, He XQ, Zeng QJ, et al. An optimal ablative margin of small single hepatocellular carcinoma treated with image-guided percutaneous thermal ablation and local recurrence prediction base on the ablative margin: a multicenter study. J Hepatocell Carcinoma 2021; 8:1375-1388.
doi: 10.2147/JHC.S330746 |
[14] |
Chen TC, Ng KF, Kuo T. Intrahepatic cholangiocarcinoma with lymphoepithelioma-like component. Mod Pathol 2001; 14:527-532.
doi: 10.1038/modpathol.3880342 |
[15] |
Jeng YM, Chen CL, Hsu HC. Lymphoepithelioma-like cholangiocarcinoma: An Epstein-Barr virus-associated tumor. Am J Surg Pathol 2001; 25:516-520.
doi: 10.1097/00000478-200104000-00012 pmid: 11257627 |
[16] | Ling W, Lu C, Huang H, Qiu T, Lu Q, Huang C, et al. Ultrasonographic findings of intrahepatic lymphoepithelioma-like cholangiocarcinoma associated with Epstein-Barr virus: Two cases report. Medicine 2019; 98:e14206. |
[17] | Zhang X, Wang N, Wei W, Li Y. Epstein-Barr virus infection-associated cholangiocarcinoma: A report of one case and the review of literature. Virol J 2022; 19:133. |
[18] | Chen G, Liu WQ, He ZZ, Liao XM, Xie YH. Contrast-enhanced ultrasound features of lymphoepithelioma-like cholangiocarcinoma with multiple metastases: A case report. AUDT 2022; 6:122-124. |
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