Advanced Ultrasound in Diagnosis and Therapy ›› 2023, Vol. 7 ›› Issue (4): 405-408.doi: 10.37015/AUDT.2023.220049

• Case Reports • Previous Articles     Next Articles

An Epstein-Barr Virus Positive Lymphoepithelioma-Like Cholangiocarcinoma in A Young Woman with Chronic Hepatitis B Treated through Microwave Ablation: A Case Report and Literature Review

Lanxia Zhang, MMa, Qingjing Zeng, MDa, Guanghui Guo, MMa, Xuqi He, MMa, Kai Li, MDa,*()   

  1. aDepartment of Ultrasound, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
  • Received:2022-12-22 Revised:2023-03-09 Accepted:2023-05-09 Online:2023-12-30 Published:2023-10-23
  • Contact: Kai Li, MD,


Lymphoepithelioma-like cholangiocarcinoma (LELCC) is a rare subtype of carcinoma that is poorly reported. We report a case of LELCC in a 28-year-old female with chronic hepatitis B. She underwent secondary microwave ablation for residual tumor following the failure of radiofrequency ablation (RFA). Image fusion technology was used to accurately diagnose that the second lesion represented residual tumor. This case is the second successful application of microwave ablation in the treatment of LELCC. We first reviewed the ultrasonographic features of LELCC. We report this case to improve our understanding of this disease and provide evidence for its clinical treatment.

Key words: Lymphoepithelioma-like cholangiocarcinoma; Microwave ablation; Ultrasound