Advances in the Application of New Ultrasound Technology for the Diagnosis and Treatment of Lymphoma

doi:10.37015/AUDT.2025.240025

Abstract

Abstract:

Lymphoma is a common hematological malignancy with markedly increasing incidence. Its pathological types are complex and heterogeneous, and there are significant differences in treatment options and efficacy. Therefore, early and precise diagnosis, assessment of efficacy, and judgment of prognosis are key clinical problems. Ultrasound (US) has important clinical value in the diagnosis and treatment of lymphoma. This article reviews the progress made with new US technologies in improving the accuracy of diagnosis and staging of lymphoma, predicting the course of lymphoma, monitoring the progression of lesions during treatment, and assisting clinics in formulating accurate and effective treatment plans. In addition, we review the biological basis of US prediction of lymphoma and provide an outlook for future research directions.

Key words: Ultrasound technology; Lymphoma; Diagnosis; Treatment

Bao Rui, Chen Lu, Luo Yukun, Zhang Mingbo. Advances in the Application of New Ultrasound Technology for the Diagnosis and Treatment of Lymphoma. Advanced Ultrasound in Diagnosis and Therapy, 2025, 9(1): 32-40.

Figures/Tables 6

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References 66

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Source	Country	Model	No. of Centers	No. Of Patients	Ultrasound image	AUC	ACC	SENS	SPEC
Liu et al. (2022) [67]	China	LASSO-Vote-SVM	6	1105	BUS	0.602	0.783	0.225	0.918
Lyu et al. (2024) [56]	China	GBM classifier	1	160	BUS	0.840	0.680	0.625	0.820
Shi et al. (2019) [68]	China	Adaboost	1	248	BUS+RTE	0.930	0.730	NA	NA
Zhu et al. (2022) [69]	China	CLA-HDM	3	763	BUS+CDFI	Internal (0.873) External 1 (0.837) External 2 (0.840)	Internal (0.871) External 1 (0.829) External 2 (0.859)	Internal (0.743) External 1 (0.657) External 2 (0.717)	Internal (0.914) External 1 (0.886) External 2 (0.906)