Advanced Ultrasound in Diagnosis and Therapy ›› 2021, Vol. 5 ›› Issue (3): 254-257.doi: 10.37015/AUDT.2021.210018

• Case Reports • Previous Articles     Next Articles

Contrast-enhanced Ultrasound Assessment of Treatment Response in a Patient with Multifocal Hepatocellular Carcinoma Treated with Transarterial Chemo and Radioembolization

Esika Savsania, Mohamed Tantawi, MDa, Corinne E. Wessner, MBA, RDMS, RVTa, Philip Lee, MDa, Andrej Lyshchik, MD, PhDa, Kevin Anton, MD, PhDa, Colette M. Shaw, MDa, Ji-Bin Liu, MDa, John R. Eisenbrey, PhDa,*()   

  1. aDepartment of Radiology, Thomas Jefferson University, Philadelphia, PA, USA
  • Received:2021-07-01 Revised:2021-07-22 Online:2021-09-30 Published:2021-08-31
  • Contact: John R. Eisenbrey, PhD,


Minimally invasive locoregional therapies have become important treatment options for patients with intermediate or late-stage hepatocellular carcinoma (HCC) who are ineligible for surgical resection or liver transplantation. Imaging modalities are essential for procedural guidance and for assessing treatment response thereafter. We report a unique finding of a patient with multifocal HCC treated with transarterial radioembolization (TARE) with yttrium-90 (Y90) and transarterial chemoembolization (TACE). We compared contrast-enhanced ultrasound (CEUS) with contrast-enhanced magnetic resonance imaging (CE-MRI) in the evaluation of treatment response to demonstrate advantages of CEUS imaging technique and its early detection of viable tumor.

Key words: Contrast-enhanced ultrasound; Hepatocellular carcinoma; Transarterial radioembolization; Transarterial chemoembolization; Treatment response