Advanced Ultrasound in Diagnosis and Therapy ›› 2019, Vol. 3 ›› Issue (4): 187-192.doi: 10.37015/AUDT.2019.191220

• Original Research • Previous Articles     Next Articles

Differences Between Type I and Type II Papillary Renal Cell Carcinoma on Ultrasound

Qing Zhang, MDa, Shuping Wei, MDb, Bin Yang, MDb, Xiaoqin Qian, MDa,*()   

  1. a Department of Ultrasonography, Affiliated People’s Hospital of Jiangsu University, Zhenjiang, Jiangsu, China
    b Department of Ultrasonography, Jinling Hospital, Nanjing, Jiangsu, China
  • Received:2019-09-09 Online:2019-12-30 Published:2019-12-25
  • Contact: Xiaoqin Qian, MD,


Objective: To identify the characteristics and differences between type I and type II papillary renal cell carcinoma (PRCC) using ultrasound.
Methods: Twenty-five patients with PRCC, including 16 cases of type I and 9 cases of type II PRCC, were enrolled in this study. All lesions were surgically resected and pathologically confirmed. A conventional ultrasound and a contrast-enhanced ultrasound were performed on each of the 25 patients with PRCC before the operation. Both ultrasounds were performed by a single highlyqualified doctor with more than 10 years of experience. Features, including maximum diameter, boundary, shape, and growth pattern of the mass, color Doppler flow image (CDFI), enhancement pattern, degree, and uniformity, arrival time; and time to peak, obtained from the conventional and contrast-enhanced ultrasounds, were analyzed and compared between type I and type II PRCC.
Results: On conventional ultrasound, type II PRCCs were significantly larger (P = 0.000), less clear (P = 0.001) and more irregular (P = 0.004) than type I PRCCs. There was also a statistically significant difference in growth pattern (P = 0.019) and enhancement uniformity (P = 0.016) between type I and II PRCC.
Conclusion: There are statistically significant differences in sonographic features between the two types of PRCC. This knowledge could assist clinicians when choosing surgical procedures.

Key words: Papillary renal cell carcinoma; Pathology; Ultrasound; Contrast-enhanced ultrasound