Advanced Ultrasound in Diagnosis and Therapy ›› 2023, Vol. 7 ›› Issue (1): 42-46.doi: 10.37015/AUDT.2023.220005

• Case Reports • Previous Articles     Next Articles

Prenatal Ultrasound Diagnosis of Giant Cystic Meconium Peritonitis in Fetus Following in Vitro Fertilization: A Case Report

Yixin Zhang, MSa, Yuli Zhao, MSa, Yuwen Su, MSb, Sen Wang, MSa, Li Feng, MDa,*()   

  1. a Department of Medical Ultrasound, Shandong First Medical University, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qian Foshan Hospital, Shandong Medicine and Health Key Laboratory of Abdominal Medical Imaging, Jinan, Shandong, China
    b Department of Radiology, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong, China
  • Received:2022-02-23 Accepted:2022-03-25 Online:2023-03-30 Published:2023-03-30
  • Contact: Li Feng, MD,


The incidence of giant cystic meconium peritonitis (GCMP) in pregnancies following artificial reproductive techniques is rare. We report the first case of GCMP following in vitro fertilization and embryo transfer in China. A 32-year-old woman with a history of bilateral salpingectomy due to ectopic pregnancy attended our in vitro fertilization and embryo transfer program. Meconium peritonitis, polyhydramnios, bowel dilatation, and intra-abdominal calcification were detected by ultrasound at 33 weeks of gestation. Cesarean section due to scarred uterus was performed at 35+1 weeks of gestation. A normal female infant with a distended abdomen was delivered. Emergency laparotomy was performed on the female infant because of the presence of a giant abdominal mass. A 0.2-cm perforation was found in the ileum. Enterostomy could not be performed due to the heavy adhesion. Prenatal diagnosis of meconium peritonitis is possible through careful ultrasonographic examination, and prognosis can be improved through early surgical intervention and intensive postoperative support.

Key words: Embryo transfer; Meconium peritonitis; Prenatal diagnosis; Ultrasonography