Neurofibromatosis with Intrahepatic, Retroperitoneal and Pelvic Involvement: A Case Report and Literature Review

doi:10.37015/AUDT.2021.200066

Advanced Ultrasound in Diagnosis and Therapy ›› 2022, Vol. 6 ›› Issue (1): 29-32.doi: 10.37015/AUDT.2021.200066

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Neurofibromatosis with Intrahepatic, Retroperitoneal and Pelvic Involvement: A Case Report and Literature Review

Danqing Huang, MS^a, Min Tang, MS^b, Aimei Li, MD^c, Decai Yu, MD^d, Jun Chen, MD^e, Min Wu, MS^a, Wenping Wang, MD^f, Wentao Kong, MD^a^,^*()

^aDepartment of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, China
^bDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China
^cDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, China
^dDepartment of Hepatobiliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, China
^eDepartment of Pathology, Zhongshan Hospital, Fudan University, Shanghai, China
^fDepartment of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, China

Received:2020-11-22 Revised:2020-12-21 Online:2022-03-30 Published:2022-03-01
Contact: Wentao Kong, MD, E-mail:breezewen@163.com

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Abstract

Abstract:

Neurofibromatosis type 1 (NF1) is a benign peripheral nerve sheath tumor, which can primarily cause neurocutaneous manifestations. We herein present a rare case of periportal neurofibromatosis with intrahepatic, retroperitoneal and pelvic involvement. The patient underwent abdominal ultrasound (US), magnetic resonance imaging, and a positron emission tomography-computed tomography. Despite these various imaging features, a diagnosis of lymphomas could not be entirely excluded. The patient therefore underwent US-guided biopsy, and a diagnosis of intrahepatic neurofibromatosis was made. Through retrospective analysis of this case along with literature review, we concluded that distributing along the Glisson’s sheath may be a characteristic in the diagnosis of NF that involves liver.

Key words: Case report; Ultrasonography; Radiology; Neurofibromatosis; Glisson’s sheath

Danqing Huang, MS, Min Tang, MS, Aimei Li, MD, Decai Yu, MD, Jun Chen, MD, Min Wu, MS, Wenping Wang, MD, Wentao Kong, MD. Neurofibromatosis with Intrahepatic, Retroperitoneal and Pelvic Involvement: A Case Report and Literature Review. Advanced Ultrasound in Diagnosis and Therapy, 2022, 6(1): 29-32.

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Neurofibromatosis with Intrahepatic, Retroperitoneal and Pelvic Involvement: A Case Report and Literature Review

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