Advanced Ultrasound in Diagnosis and Therapy ›› 2023, Vol. 7 ›› Issue (4): 348-355.doi: 10.37015/AUDT.2023.230045

• Review Articles • Previous Articles     Next Articles

Arterial Stiffness and Cardiovascular Risk: The Role of Brachial Cuff-measured Index

Lin Jin, MDa,1, Xinyi Li, BSb,1, Mengjiao Zhang, MSc,1, Xujie Zhang, BSd, Chaoyu Xian, BSe, Fuyou Liang, PhDf,*(), Zhaojun Li, MDc,f,*()   

  1. aDepartment of Ultrasound, Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
    bBusiness School, Hubei University, Wuhan, China
    cDepartment of Ultrasound, Jiading Branch of Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
    dDepartment of Engineering Mechanics, School of Naval Architecture, Ocean & Civil Engineering, Shanghai Jiao Tong University, Shanghai, China
    eDawai Healthcare Co.,Ltd, China
    fDepartment of Ultrasound, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
  • Received:2023-07-15 Revised:2023-08-14 Accepted:2023-09-04 Online:2023-12-30 Published:2023-10-23
  • Contact: Department of Ultrasound, Jiading Branch of Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 800 Huangjiahuayuan Road, Jiading District, Shanghai 201803, P.R. China; Department of Engineering Mechanics, School of Naval Architecture, Ocean & Civil Engineering, Shanghai Jiao Tong University, Shanghai, China. e-mail: lzj_1975@sina.com;fuyouliang@sjtu.edu.cn,
  • About author:Lin Jin, Xinyi Li and Mengjiao Zhang contributed equally to this study.

Abstract:

Early detection of vascular disease is fundamental to the prevention and treatment of systemic vascular lesions. The timely identification of vascular damage can be achieved by comprehensively assessing the structural anomaly and/or functional degeneration of the vasculature. The assessment may to some extent indicate the long-term detrimental effects of cardiovascular disease (CVD) risk factors on vascular health. A key aspect in the evaluation of vascular function is the measurement of arterial stiffness. In 2012, the arterial velocity-pulse index (AVI) and arterial pressure-volume index (API) were introduced, which are noninvasively measured with a brachial cuff, and can reflect the status of arterial stiffness in both the aorta and the brachial artery. A large number of relevant studies have demonstrated the strong associations between AVI/API and various CVD risk factors, underlining the substantial relevance of the indices in CVD risk assessment. In this review, we provide a systematic review of the progresses made in brachial cuff-based measurements of arterial stiffness. In addition, we summarize the results of the recent studies focused on exploring the associations of AVI/API with relevant risk factors as well as their roles in CVD assessment.

Key words: Arterial stiffness; Cardiovascular risk; Brachial cuff; Arterial velocity-pulse index; Arterial pressure-volume index