Many kinds of skin masses appeared as well-defined hypoechogenic lesion in ultrasound. Higher-frequency sound waves enable high resolution observation of the anatomical level and internal echogenic, In this study, 4 typical cases were observed by utilizing high resolution ultrasound (HRUS) at 10 to 20 MHz Ultrasound shows most Basal cell carcinoma (BCC ) was irregular-shaped while other kinds of cases appear as oval-shape, meanwhile, epidermoid cyst was located in the subcutaneous layer while the other three kinds of masses were located in the dermis. Color Doppler shows eccrine poromas and BCCs have flow signals, while dermatofibromas and eccrine poromas show a lack of vascularity. HRUS can provide noninvasive and effective diagnostic information for skin masses before surgery and can help the clinician evaluate whether the tumor was completely removed after surgery.