Ultrasound-guided percutaneous trans-hepatic intestinal drainage is a rare intervention operation at home and broad.We report this case of percutaneous trans-hepatic intestinal drainage because of its mechanic intestinal obstruction. A 61-year-old woman was admitted to our hospital for abdominal distension, stomachache, vomit. The symptoms could not be alleviated by routine fast and nasogastric tube. She had received pancreaticoduodenectomy as a result of carcinoma of pancreatic head three months before this hospital visit. T-tube angiography showed obvious afferent loop obstruction and ultrasonography demonstrated dilated proximal intestines. Considering her poor laboratory results, we put a pigtail into the patient’s dilated proximal intestines instead of administering laparotomy to alleviate intestinal pressure in a short time. Our case mainly stresses the feasibility of ultrasound-guided percutaneous trans-hepatic catheter intestinal decompression in special circumstances.