The Value of CEUS in the Diagnosis and Treatment of Thyroid Primary Squamous Cell Carcinoma: A Case Report

Yiming Li, BM; Jing Xiao, MD; Fang Xie, MD; Yu Lin, BM; Mingbo Zhang, MD; Yukun Luo, MD

doi:10.37015/AUDT.2023.220027

ADVANCED ULTRASOUND IN DIAGNOSIS AND THERAPY >

2023 , Vol. 7 >Issue 4: 412 - 415

DOI: https://doi.org/10.37015/AUDT.2023.220027

Case Reports

The Value of CEUS in the Diagnosis and Treatment of Thyroid Primary Squamous Cell Carcinoma: A Case Report

Yiming Li, BM ,
Jing Xiao, MD ,
Fang Xie, MD ,
Yu Lin, BM ,
Mingbo Zhang, MD ,
Yukun Luo, MD

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^aDepartment of Ultrasound, the First Medical Center of PLA General Hospital, Beijing, China
^bDepartment of pathology, the First Medical Center of PLA General Hospital, Beijing, China

Department of Ultrasound, the First Medical Center of PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, China. e-mail: owsifanduizhe@126.com;

Received date: 2022-07-24

Revised date: 2022-10-02

Accepted date: 2022-10-05

Online published: 2023-10-23

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Abstract

Primary squamous cell carcinoma of the thyroid (PSCCT) is a rare clinical disease characterized by rapid growth, high invasiveness, and a poor prognosis. A 66-year-old male patient was admitted due to throat pain and dysphagia. Ultrasound revealed a calcified hypoechoic mass in the right lobe of the thyroid gland, measuring approximately 35.3 ml. Ultrasound and PET-CT both indicated high suspicion of malignancy. The patient underwent contrast-enhanced US-guided biopsy, and the pathological results revealed poorly differentiated squamous cell carcinoma. CEUS was performed regularly during the Chemotherapy combined with pembrolizumab (PD-1) treatment courses. The vital area was significantly reduced with neither recurrence nor cervical lymph node metastasis. Surgical resection and chemotherapy combined with immunotherapy had a significant treatment effect in this case. CEUS is helpful for diagnosis confirmation, biopsy guidance and efficacy evaluation and has important clinical application value.

Key words： Ultrasonography; Image enhancement; Thyroid gland; Squamous cell carcinoma; Biopsy

Cite this article

Yiming Li, BM , Jing Xiao, MD , Fang Xie, MD , Yu Lin, BM , Mingbo Zhang, MD , Yukun Luo, MD . The Value of CEUS in the Diagnosis and Treatment of Thyroid Primary Squamous Cell Carcinoma: A Case Report[J]. ADVANCED ULTRASOUND IN DIAGNOSIS AND THERAPY, 2023 , 7(4) : 412 -415 . DOI: 10.37015/AUDT.2023.220027

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