Original Research

The Value of VTTQ Combined with B-mode US for Distinguishing Benign from Malignant Breast Masses by Comparing with SE: A Clinical Research

  • Lujing Li, MD ,
  • Zuofeng Xu, MD
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  • aDepartment of Ultrasound, the Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, China
Department of Ultrasound, the Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, China. e-mail: lilujing@mail2.sysu.edu.cn

Received date: 2022-11-15

  Revised date: 2023-02-15

  Accepted date: 2023-03-21

  Online published: 2023-10-23

Abstract

Objective The purpose of this study was to compare the diagnostic performance of virtual touch tissue quantification (VTTQ) combined with B-mode ultrasonograpgy (US), strain elastography (SE) combined with B-mode US and B-mode US alone in differentiating the properties of breast lesions.

Methods A retrospective database was queried for 283 healthy subjects and 100 consecutive patients with 130 breast lesions. All the cases were examined by B-mode US, VTTQ and SE. Histological diagnosis was used as the reference standard. The area under the receiver operating curve (AUC) values of each data set was compared.

Results Twenty-two lesions were determined as malignant and 108 as benign. The best cutoff point of VTTQ was 7.82 m/s. The AUC of B-mode US combined with VTTQ or SE was greater than that of B-mode US alone (0.913 or 0.918 vs. 0.797) (P = 0.007 and 0.012).

Conclusion Both VTTQ and SE could give help to B-mode US in distinguishing benign from malignant breast lesions about elastography values. There was no difference between them.

Cite this article

Lujing Li, MD , Zuofeng Xu, MD . The Value of VTTQ Combined with B-mode US for Distinguishing Benign from Malignant Breast Masses by Comparing with SE: A Clinical Research[J]. ADVANCED ULTRASOUND IN DIAGNOSIS AND THERAPY, 2023 , 7(4) : 394 -400 . DOI: 10.37015/AUDT.2023.220041

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