ADVANCED ULTRASOUND IN DIAGNOSIS AND THERAPY >
The Value of VTTQ Combined with B-mode US for Distinguishing Benign from Malignant Breast Masses by Comparing with SE: A Clinical Research
Received date: 2022-11-15
Revised date: 2023-02-15
Accepted date: 2023-03-21
Online published: 2023-10-23
Objective The purpose of this study was to compare the diagnostic performance of virtual touch tissue quantification (VTTQ) combined with B-mode ultrasonograpgy (US), strain elastography (SE) combined with B-mode US and B-mode US alone in differentiating the properties of breast lesions.
Methods A retrospective database was queried for 283 healthy subjects and 100 consecutive patients with 130 breast lesions. All the cases were examined by B-mode US, VTTQ and SE. Histological diagnosis was used as the reference standard. The area under the receiver operating curve (AUC) values of each data set was compared.
Results Twenty-two lesions were determined as malignant and 108 as benign. The best cutoff point of VTTQ was 7.82 m/s. The AUC of B-mode US combined with VTTQ or SE was greater than that of B-mode US alone (0.913 or 0.918 vs. 0.797) (P = 0.007 and 0.012).
Conclusion Both VTTQ and SE could give help to B-mode US in distinguishing benign from malignant breast lesions about elastography values. There was no difference between them.
Lujing Li, MD , Zuofeng Xu, MD . The Value of VTTQ Combined with B-mode US for Distinguishing Benign from Malignant Breast Masses by Comparing with SE: A Clinical Research[J]. ADVANCED ULTRASOUND IN DIAGNOSIS AND THERAPY, 2023 , 7(4) : 394 -400 . DOI: 10.37015/AUDT.2023.220041
[1] | Hoffmann R, Reich C, Skerl K. Evaluating different combination methods to analyse ultrasound and shear wave elastography images automatically through discriminative convolutional neural network in breast cancer imaging. Int J Comput Assist Radiol Surg 2022; 17:2231-2237. |
[2] | Masroor I, Ahmed MN, Pash S. To evaluate the role of sonography as an adjunct to mammography in women with dense breasts. J Pak Med Assoc 2009; 59:298-301. |
[3] | Maskarinec G, Meng L, Ursin G. Ethnic differences in mammographic densities. Int J Epidemiol 2001; 30:959-965. |
[4] | American College of Radiology. Breast imaging reporting and data system, Breast imaging atlas. fifth ed. Reston 2013 |
[5] | Margolin FR, Leung JW, Jacobs RP, Denny SR. Percutaneous imaging-guided core breast biopsy: 5 years’ experience in a community hospital. AJR Am J Roentgenol 2001; 177:559-564. |
[6] | Wiratkapun C, Bunyapaiboonsri W, Wibulpolprasert B, Lertsithichai P. Biopsy rate and positive predictive value for breast cancer in BI-RADS category 4 breast lesions. J Med Assoc Thai 2010; 93:830-837. |
[7] | Matsumoto K, Miyaaki H, Fukushima M, Sasaki R, Haraguchi M, Miuma S, Nakao K. The impact of single-nucleotide polymorphisms on liver stiffness and controlled attenuation parameter in patients treated with direct-acting antiviral drugs for hepatitis C infection. Biomed Rep 2022; 16:9. |
[8] | Sigrist RMS, El Kaffas A, Jeffrey RB, Rosenberg J, Willmann JK. Intra-individual comparison between 2-D shear wave elastography (GE System) and virtual touch tissue quantification (Siemens System) in grading liver fibrosis. Ultrasound Med Biol 2017; 43:2774-2782. |
[9] | Bai M, Du L, Gu J, Li F, Jia X. Virtual touch tissue quantification using acoustic radiation force impulse technology: Initial clinical experience with solid breast masses. J Ultrasound Med 2012; 31:289-294. |
[10] | Zhi H, Ou B, Xiao XY, Peng YL, Wang Y, Liu LS, et al. Ultrasound elastography of breast lesions in Chinese women: A multicenter study in China. Clin Breast Cancer 2013; 13:392-400. |
[11] | Tanter M, Bercoff J, Athanasiou A, Deffieux T, Gennisson JL, Montaldo G, et al. Quantitative assessment of breast lesion viscoelasticity: Initial clinical results using supersonic shear imaging. Ultrasound Med Biol 2008; 34:1373-1386. |
[12] | Tozaki M, Isobe S, Fukuma E. Preliminary study of ultrasonographic tissue quantification of the breast using the acoustic radiation force impulse (ARFI) technology. Eur J Radiol 2011; 80:e182-e187. |
[13] | Wojcinski S, Brandhorst K, Sadigh G, Hillemanns P, Degenhardt F. Acoustic radiation force impulse imaging with Virtual Touch? tissue quantification: mean shear wave velocity of malignant and benign breast masses. Int J Womens Health 2013; 5:619-627 |
[14] | Tamaki K, Tamaki N, Kamada Y, Uehara K, Miyashita M, Ishida T, et al. A non-invasive modality: the US Virtual Touch Tissue Quantification (VTTQ) for evaluation of breast cancer. Jpn J Clin Oncol 2013; 43:889-895. |
[15] | Berg WA, Cosgrove DO, Doré CJ, Sch?fer FK, Svensson WE, Hooley RJ, et al. Shear-wave elastography improves the specificity of breast US: The BE 1 multinational study of 939 masses. Radiology 2012;262: 435-449. |
[16] | Youk JH, Son EJ, Gweon HM, Kim H, Park YJ, Kim JA. Comparison of strain and shear wave elastography for the differentiation of benign from malignant breast lesions, combined with B-mode ultrasonography: qualitative and quantitative assessments. Ultrasound Med Biol 2014; 40:2336-2344. |
[17] | Hou XJ, Sun AX, Zhou XL, Ji Q, Wang HB, Wei H, et al. The application of Virtual Touch tissue quantification (VTQ) in diagnosis of thyroid lesions: A preliminary study. Eur J Radiol 2013; 82:797-801. |
[18] | Chang JM, Moon WK, Cho N, Kim SJ. Breast mass evaluation: factors influencing the quality of US elastography. Radiology 2011; 259:59-64 |
/
〈 | 〉 |