ADVANCED ULTRASOUND IN DIAGNOSIS AND THERAPY >

2018 , Vol. 2 >Issue 2: 128 - 132

DOI: https://doi.org/10.37015/AUDT.2018.180811

Original Research

Ultrasound Characteristics of Kimura Disease: Retrospective Analysis of 30 cases

  • Liu, MD Bingyan ,
  • Fu, MD Shaoqing ,
  • Luo, MD Dongni ,
  • Fu, MD Shengxin ,
  • Wang, MD Donglin ,
  • Liao, MD Wei
Expand
  • Department of ultrasonography, Hainan General Hospital, Haikou, Hainan, China

Received date: 2018-07-01

  Online published: 2018-08-19

Fold

Abstract

Objective: To demonstrate the characteristics of the lesion in Kimura disease on ultrasound imaging and compare with clinical features in patients with pathologically-approved Kimura disease.
Methods: A total of 30 patients (29 men and 1 woman; a mean age of 35.4 years) with Kimura disease confirmed by surgery and pathology were enrolled in the study. Ultrasonographic findings were analyzed retrospectively and compared with clinical features and laboratory examinations to better understand the relationship among them.
Results: All patients presented with painless, progressively enlarged soft tissue masses in head and neck, axillary, inguinal regions or limb extremities. Laboratory results showed elevation of eosinophils in both peripheral blood and serum IgE in 12 of 30 cases. Ultrasound findings of the lesions in Kimura disease were divided into three types: Type I: characterized by simple lymph node enlargement; Type II: characterized by flake-like thickening of the lesion without mass effect, and enlargement of nearby lymph nodes; Type III: a tumor-like lesion associate with enlargement of nearby lymph nodes.
Conclusion: The Kimura disease has specific ultrasonographic characteristics of lymph node and adjacent structures. When combined with patient’s clinical information and laboratory tests, ultrasound examination can provide useful information for making clinical diagnosis and management.

Key words： Kimura disease; eosinophilic lymphogranuloma; ultrasound

Cite this article

Liu, MD Bingyan , Fu, MD Shaoqing , Luo, MD Dongni , Fu, MD Shengxin , Wang, MD Donglin , Liao, MD Wei . Ultrasound Characteristics of Kimura Disease: Retrospective Analysis of 30 cases[J]. ADVANCED ULTRASOUND IN DIAGNOSIS AND THERAPY, 2018 , 2(2) : 128 -132 . DOI: 10.37015/AUDT.2018.180811

References

[1] Kimm HT, Szeto C. Eosinophilic hyperplastic lymphogranuloma, comparison with Mikulicz's disease. Chin Med J 1937; 23:699-700.
[2] Kimura T, Yoshimura S, Ishikawa E. Unusual granulation combined with hyperplastic change of lymphatic tissue. Trans Soc Pathol Jpn 1948; 37:179-80.
[3] Chang AR, Kim K, Kim HJ, Kim IH, Park CI, Jun YK. Outcomes of Kimura's disease after radiotherapy or nonradiotheraputic treatment modalities. Int J Radial Oncol Biol Phys 2006; 65:1233-9.
[4] Kabashima R, Kabashima K, Mukumoto S, Hino R, Huruno Y, Kabashima N, et al. Kimura's disease presenting with a giant suspensory tumor and associated with membrane proliferative. Glomera lonephritis. Eur J Dematic 2009; 19:626-8.
[5] Ye P, Ma DQ, Gao Y, Peng X. Comparison of the efficacy of different treatment modalities for Kimura's disease. Int J Oral Maxillofac Surg 2017; 46:350-4.
[6] Wang F, Lu Z, Lu W, Li C, Mo X, Yang F, et al. The ultrasonic and clinical features of Kimura's disease. Chin J Diagnostics (Electronic Edition) 2016; 4:90-3.
[7] Shin GW, Lee SJ, Choo HJ, Park YM, Jeong HW, Lee SM, et al. Ultrasonographic findings of Kimura's disease presenting in the upper extremities. Jpn J Radiol 2014; 32:692-9.
[8] Jung J, Han JH, Park SY. Kimura's disease as a solitary intrapulmnary lymphadenopathy. Eur J Cardiothorac Surg 2016; 50:183-4.
[9] Chen H, Chen H, Zhang N, Yang Q, Fang L, Sun F, et al. A case of Kimura disease developed into cutaneous T-cell lymphoma in 38 years. Chin J Hematol 2007; 28:271-2.
[10] Fatani HA, AL-Mutrafi A, AL-Qahtani KH, Tunio MA. Co-existence of lip and epiglottis Kimura's disease. Saudi Med J 2015; 36:1226-8.
[11] Baba A, Ojiri H, Dogru M, Tanaka Y, Takahashi S, Mogami T, et al. An unusual clinical presentation of kimura disease manifesting with a typical cephalocervical lesion and an atypical subcutaneous hip mass lesion. Intern Med 2016; 55:1017-20.
[12] Jin Y, Zhao R, Zhao L. Pathological diagnosis and differential diagnosis of eosinophilic lymphogranuloma. Chin J of clinical and experimental pathology 1999; 15:458-60.
[13] Yang L. A contrast observation between Kimura's disease and angiolymphoid hyperplasia with eosinophilia-A report of 6 cases and review of literature. Chin J Diagnostics Pathology 1996; 3:216-8.
[14] Olsen TG, Helwig EB. Angiolymphoid hyperplasia with eosinophilis: a clinicopathologic study of 116 patients. J Am Acad Dermatol 1985; 12:781.
[15] Lu L, Chen R, Li X, Wang J. Kimura disease and epitheliod hemangioma: a comparative study of 12 cases. Chin J Pathol 2005; 34:353-7.
[16] Chong WS, Thomas A, Goh CL. Kimura's disease and angiolymphoid hyperplasia with eosinophilia: two disease entities in the same patient: case report and review of the literature. Int J Dermatol 2006; 45:139-45.
[17] Wang H, Fang F, Sun Y, Wang S, Mao Y. Concurrent Kimura disease and lupus nephritis: A case report. Medicine (Baltimore) 2016; 95:e5086.
[18] Huang W, Tang L, Shen Y, Zhang N, Ni S, Xie W, et al. Diagnostic value of Kimura’s disease with ultrasonography. Natl Med J China 2015; 95:3054-6.
Options
Outlines

/

〈 〉

Content
For Authors
For Reviewers
Article Category
Publisher Policies
About
Top 10 Rankings

Share: WeChat

Copyright ©2018 Advanced Ultrasound in Diagnosis and Therapy

|

Creative Commons License Advanced Ultrasound in Diagnosis and Therapy (AUDT)  is licensed under a Creative Commons Attribution 4.0 International License.