ADVANCED ULTRASOUND IN DIAGNOSIS AND THERAPY >
Application and Progress of Ultrasound Technology in Atherosclerosis
Received date: 2022-08-16
Accepted date: 2022-10-12
Online published: 2023-03-30
Atherosclerosis (AS) is the main pathophysiological process behind CVD. Cardiovascular diseases caused by AS (such as stroke, coronary heart disease, etc.) are characterized by a high prevalence, high disability rate and high mortality, which greatly increase the burden on families and society. Thus, it is important to find AS as early as possible. When atherosclerosis occurs, the earliest sign of its structural and functional changes is arterial stiffness, and endothelial dysfunction is the key link. Arteriosclerosis is caused by the imbalance between collagen and elastin in the arteries. Elastin fibers gradually decrease, and stiffer collagen fibers increase, making the vessels less elastic. Endothelial dysfunction also affects the regulatory function of arterial vascular tension, and accelerates the remodeling of the vascular wall, to make blood vessels more rigid. Quantitative measurement of arterial stiffness and carotid intima-media thickness (CIMT) is an important tool for early detection of vascular lesions. At present, ultrasound technology including echo tracking (ET), wave intensity (WI), real-time shear wave elastography (SWE), ultrafast pulse wave velocity (ufPWV), shear wave dispersion (SWD), cardio-ankle vascular index (CAVI), arterial velocity pulse index and arterial pressure volume index (AVI and API) has the advantages of being noninvasive, real-time, economical and reproducible in the assessment of atherosclerosis, and is widely used in the early diagnosis of AS. Most importantly, the change in arterial hardness detected by traditional ultrasound technology precedes the change in intima-media thickness, suggesting that ultrasonic elasticity monitoring may be a more sensitive method of predicting AS and can find and prevent cardiovascular diseases earlier.
Qiaoer Gong, BS , Nianyu Xue, MS . Application and Progress of Ultrasound Technology in Atherosclerosis[J]. ADVANCED ULTRASOUND IN DIAGNOSIS AND THERAPY, 2023 , 7(1) : 8 -15 . DOI: 10.37015/AUDT.2023.220030
| [1] | Kobayashia K, Akishita M, Yu W, Hashimoto M, Ohni M, Toba K. Interrelationship between non-invasive measurements of atherosclerosis: flow-mediated dilation of brachial artery, carotid intima-media thickness and pulse wave velocity. Atherosclerosis 2004; 173:13-18. |
| [2] | Iino H, Okano T, Daimon M, Sasaki K, Chigira M, Nakao T, et al. Usefulness of carotid arterial strain values for evaluating the arteriosclerosis. J Atheroscler Thromb 2019; 26:476-487. |
| [3] | Tomiyama H, Yamashina A. Non-invasive vascular function tests: their pathophysiological background and clinical application. Circ J 2010; 74:24-33 |
| [4] | Duca L, Blaise S, Romier B, Laffargue M, Gayral S, El Btaouri H, et al. Matrix ageing and vascular impacts: focus on elastin fragmentation. Cardiovasc Res 2016; 110:298-308. |
| [5] | Xu C, Zarins CK, Pannaraj PS, Bassiouny HS, Glagov S. Hypercholesterolemia superimposed by experimental hypertension induces differential distribution of collagen and elastin. Arterioscler Thromb Vasc Biol 2000; 20:2566-2572. |
| [6] | Kumrular M, Karaca Ozer P, Elitok A. The role of aortic stiffness parameters in evaluating myocardial ischemia. Cardiol Res 2020; 11:328-336. |
| [7] | Li Z, Huang H, Huang L, Du L, Sun Y, Duan Y. Prevention of oxidized low density lipoprotein-induced endothelial cell injury by DA-PLGA-PEG-cRGD nanoparticles combined with ultrasound. Int J Mol Sci 2017; 18:815. |
| [8] | Simionescu M. Implications of early structural-functional changes in the endothelium for vascular disease. Arterioscler Thromb Vasc Biol 2007; 27:266-274. |
| [9] | Nezu T, Hosomi N, Aoki S, Matsumoto M. Carotid intima-media thickness for atherosclerosis. J Atheroscler Thromb 2016; 23:18-31. |
| [10] | Hurst RT, Ng DW, Kendall C, Khandheria B. Clinical use of carotid intima-media thickness: review of the literature. J Am Soc Echocardiogr 2007; 20:907-914. |
| [11] | Eikendal AL, Groenewegen KA, Anderson TJ, Britton AR, Engstr?m G, Evans GW, et al. Common carotid intima-media thickness relates to cardiovascular events in adults aged < 45 years. Hypertension 2015; 65:707-713. |
| [12] | Li Z, Qin Y, Du L, Luo X. An improvement of carotid intima-media thickness and pulse wave velocity in renal transplant recipients. BMC Med Imaging 2018; 18:23. |
| [13] | Li ZJ, Liu Y, Du LF, Luo XH. Evaluating arterial stiffness in type 2 diabetes patients using ultrasonic radiofrequency. J Huazhong Univ Sci Technolog Med Sci 2016; 36:442-448. |
| [14] | Gu W, Wu J, Pei Y, Ji J, Wu H, Wu J. Evaluation of common carotid stiffness via echo tracking in hypertensive patients complicated by acute aortic dissection. J Ultrasound Med 2021; 40:929-936. |
| [15] | Yang S, Wang DZ, Zhang HX, He W, Chen BX. Echo-tracking technology assessment of carotid artery stiffness in patients with coronary slow flow. Ultrasound Med Biol 2015; 41:72-76. |
| [16] | Várady E, Feher E, Levai A, Battyany I. Estimation of vessel age and early diagnose of atherosclerosis in progeria syndrome by using echo-tracking. Clin Hemorheol Microcirc 2010; 44:297-301. |
| [17] | Liang H, Wang D, Che G, Su Y. Evaluation of carotid artery elasticity in patients with uremia by echo tracking. J Med Ultrason 2018; 45:591-596. |
| [18] | Antonini-Canterin F, Di Nora C, Pellegrinet M, Vriz O, La Carrubba S, Carerj S, et al. Effect of uric acid serum levels on carotid arterial stiffness and intima-media thickness: a high resolution Echo-Tracking Study. Monaldi Arch Chest Dis 2019; 89:37-42. |
| [19] | Parker KH, Jones CJ. Forward and backward running waves in the arteries: analysis using the method of characteristics. J Biomech Eng 1990; 112:322-326. |
| [20] | Niki K, Sugawara M, Chang D, Harada A, Okada T, Sakai R, et al. A new noninvasive measurement system for wave intensity: evaluation of carotid arterial wave intensity and reproducibility. Heart Vessels 2002; 17:12-21 |
| [21] | Niki K, Sugawara M, Chang D, Harada A, Okada T, Tanaka R. Effects of sublingual nitroglycerin on working conditions of the heart and arterial system: analysis using wave intensity. J Med Ultrason 2005; 32:145-152. |
| [22] | Saiki H, Kurishima C, Masutani S, Senzaki H. Cerebral circulation in patients with Fontan circulation: assessment by carotid arterial wave intensity and stiffness. Ann Thorac Surg 2014; 97:1394-1399. |
| [23] | Liu J, Zhang Y, Cao TS, Duan YY, Yuan LJ, Yang YL, et al. Preferential macrovasculopathy in systemic sclerosis detected by regional pulse wave velocity from wave intensity analysis: comparisons of local and regional arterial stiffness parameters in cases and controls. Arthritis Care Res 2011; 63:579-587. |
| [24] | Sugawara M, Niki K, Ohte N, Okada T, Harada A. Clinical usefulness of wave intensity analysis. Med Biol Eng Comput 2009; 47:197-206. |
| [25] | Zhang Y, Liu M, Wang M, Zhang L, Lv Q, Xie M, et al. Wave intensity analysis of carotid artery: a noninvasive technique for assessing hemodynamic changes of hyperthyroid patients. J Huazhong Univ Sci Technolog Med Sci 2010; 30:672-677. |
| [26] | Youk JH, Gweon HM, Son EJ. Shear-wave elastography in breast ultrasonography: the state of the art. Ultrasonography 2017; 36:300-309. |
| [27] | Azizi G, Keller JM, Mayo ML, Piper K, Puett D, Earp KM, et al. Thyroid nodules and shear wave elastography: a new tool in thyroid cancer detection. Ultrasound Med Biol 2015; 41:2855-2865. |
| [28] | Ferraioli G, Parekh P, Levitov AB, Filice C. Shear wave elastography for evaluation of liver fibrosis. J Ultrasound Med 2014; 33:197-203. |
| [29] | Prado-Costa R, Rebelo J, Monteiro-Barroso J, Preto AS. Ultrasound elastography: compression elastography and shear-wave elastography in the assessment of tendon injury. Insights Imaging 2018; 9:791-814. |
| [30] | Azizi G, Keller JM, Mayo ML, Piper K, Puett D, Earp KM, et al. Shear wave elastography and cervical lymph nodes: predicting malignancy. Ultrasound Med Biol 2016; 42:1273-1281. |
| [31] | Correas JM, Tissier AM, Khairoune A, Vassiliu V, Méjean A, Hélénon O, et al. Prostate cancer: diagnostic performance of real-time shear-wave elastography. J Radiology, 2015;275:280-289. |
| [32] | Bhatia K, Cho C, Tong C, Lee Y, Yuen E, Ahuja A. Shear wave elastography of focal salivary gland lesions: preliminary experience in a routine head and neck US clinic. Radiology 2012; 22:957-965. |
| [33] | Li Z, Du L, Wang F, Luo X. Assessment of the arterial stiffness in patients with acute ischemic stroke using longitudinal elasticity modulus measurements obtained with Shear Wave Elastography. Med Ultrason 2016; 18:182-189. |
| [34] | Marais L, Pernot M, Khettab H, Tanter M, Messas E, Zidi M, et al. Arterial stiffness assessment by shear wave elastography and ultrafast pulse wave imaging: comparison with reference techniques in normotensives and hypertensives. Ultrasound Med Biol 2019; 45:758-772. |
| [35] | Ramnarine KV, Garrard JW, Dexter K, Nduwayo S, Panerai RB, Robinson TG. Shear wave elastography assessment of carotid plaque stiffness: in vitro reproducibility study. Ultrasound Med Biol 2014; 40:200-209. |
| [36] | Prado-Costa R, Rebelo J, Monteiro-Barroso J, Preto AS. Ultrasound elastography: compression elastography and shear-wave elastography in the assessment of tendon injury. Insights Imaging 2018; 9:791-814. |
| [37] | Ben-Shlomo Y, Spears M, Boustred C, May M, Anderson SG, Benjamin EJ, et al. Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects. J Am Coll Cardiol 2014; 63:636-646. |
| [38] | Cavalcante J, Lima J, Redheuil A, Al-Mallah M. Aortic Stiffness. J Am Coll Cardiol 2011; 57:1511-1522. |
| [39] | Hodis S, Zamir M. Pulse wave velocity as a diagnostic index: the pitfalls of tethering versus stiffening of the arterial wall. J Biomech 2011; 44:1367-1373. |
| [40] | Lee JY, Ryu S, Lee SH, Kim BJ, KimBS, Kang JH, et al. Association between brachial-ankle pulse wave velocity and progression of coronary artery calcium: a prospective cohort study. Cardiovasc Diabetol 2015; 14:147. |
| [41] | Kim HL, Lim WH, Seo JB, Kim SH, Zo ZH, Kim MA. Prediction of cardiovascular events using brachial‐ankle pulse wave velocity in hypertensive patients. J Clin Hypertens 2020; 22:1659-1665. |
| [42] | Yasuharu T, Setoh K, Kawaguchi T, Nakayama T, Matsuda F; Nagahama study group. Brachial‐ankle pulse wave velocity and cardio‐ankle vascular index are associated with future cardiovascular events in a general population: the Nagahama Study. J Clin Hypertens 2021; 23:1390-1398. |
| [43] | Sequí-Domínguez I, Cavero-Redondo I, álvarez-Bueno C, Pozuelo-Carrascosa DP, Nu?ez de Arenas-Arroyo S, Martínez-Vizcaíno V. Accuracy of pulse wave velocity predicting cardiovascular and all-cause mortality. A systematic review and meta-analysis. J Clin Med 2020; 9: 2080. |
| [44] | Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G, et al. 2007 ESH-ESC practice guidelines for the management of arterial hypertension: ESH-ESC task force on the management of arterial hypertension. J Hypertens 2007; 25:1751-1762. |
| [45] | Laurent S, Cockcroft J, Van Bortel L, Boutouyrie P, Giannattasio C, Hayoz D, et al. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J 2006; 27: 2588-2605. |
| [46] | Rhee K, Cho Y. Artery Wall Viscoelasticity: Measurement, Assessment, and Clinical Implications. International Journal of Precision Engineering and Manufacturing 2021; 22:1157-1168. |
| [47] | Zhu ZQ, Chen LS, Wang H, Liu FM, Luan Y, Wu LL, et al. Carotid stiffness and atherosclerotic risk: non-invasive quantification with ultrafast ultrasound pulse wave velocity. Eur Radiol 2019; 29:1507-1517. |
| [48] | Li Y, Zhang J, An X, Li J, Shi S, Ma S, et al. Evaluation of carotid artery elastic function using ultrafast pulse wave velocity and related influential factors in patients with rheumatoid arthritis. Echocardiography 2022; 39:552-560. |
| [49] | Li X, Jiang J, Zhang H, Wang H, Han D, Zhou Q, et al. Measurement of carotid pulse wave velocity using ultrafast ultrasound imaging in hypertensive patients. J Med Ultrason 2017; 44:183-190. |
| [50] | Pan FS, Yu L, Luo J, Wu RD, Xu M, Liang JY, et al. Carotid artery stiffness assessment by ultrafast ultrasound imaging: feasibility and potential influencing factors. J Ultrasound Med 2018; 37:2759-2767. |
| [51] | Mirault T, Pernot M, Frank M, Couadec M, Niarrae R, Azizie M, et al. Carotid stiffness change over the cardiac cycle by ultrafast ultrasound imaging in healthy volunteers and vascular Ehlers-Danlos syndrome. J Hypertens 2015; 33:1890-1896. |
| [52] | Li Z, Shen C, Chen Q, Sha L, Luo X, Du L. Shear wave dispersion imaging for measuring carotid elasticity and viscosity. Advanced Ultrasound In Diagnosis And Therapy 2022; 6:14-21. |
| [53] | Luo X, Du L, Li Z. Ultrasound assessment of tensile stress in carotid arteries of healthy human subjects with varying age. BMC Med Imaging 2019; 19:93. |
| [54] | Shirai K, Utino J, Otsuka K, Takata M. A novel blood pressure-independent arterial wall stiffness parameter; cardio-ankle vascular index (CAVI). J Atheroscler Thromb 2006; 13:101-107. |
| [55] | Matsushita K, Ding N, Kim ED, Budoff M, Chirinos JA, Fernhall B, et al. Cardio-ankle vascular index and cardiovascular disease: Systematic review and meta-analysis of prospective and cross-sectional studies. J Clin Hypertens 2019; 21:16-24. |
| [56] | Izuhara M, Shioji K, Kadota S, Baba O, Takeuchi Y, Uegaito T, et al. Relationship of cardio-ankle vascular index (CAVI) to carotid and coronary arteriosclerosis. Circ J 2008; 72:1762-1767. |
| [57] | Sairaku A, Eno S, Hondo T, Teragawa H, Nakano Y, Matsuda K, et al. Head-to-head comparison of the cardio-ankle vascular index between patients with acute coronary syndrome and stable angina pectoris. Hypertens Res 2010; 33:1162-1166. |
| [58] | Luo X, Zhang J, Shao S, Yan M, Wu R, Du L, et al. The role of ultrasound shear wave dispersion imaging in evaluating carotid viscoelasticity: a preliminary study. Advanced Ultrasound in Diagnosis and Therapy 2019; 3:97-102. |
| [59] | Tazawa Y, Mori N, Ogawa Y, Ito O, Kohzuki M. Arterial stiffness measured with the cuff oscillometric method is predictive of exercise capacity in patients with cardiac diseases. Tohoku J Exp Med 2016; 239:127-134. |
| [60] | Wan J, Liu S, Yang Y, Wang D, Ran F, Xia S, et al. Roles of arterial pressure volume index and arterial velocity pulse index trajectories in risk prediction in hypertensive patients with heart failure with preserved ejection fraction. Clin Exp Hypertens 2020; 42:469-478. |
| [61] | Yamanashi H, Koyamatsu J, Nagayoshi M, Shimizu Y, Kawashiri SY, Kondo H, et al. Screening validity of arterial pressure-volume index and arterial velocity-pulse index for preclinical atherosclerosis in Japanese community-dwelling adults: the Nagasaki Islands Study. J Atheroscler Thromb 2018; 25:792-798. |
| [62] | Okamoto M, Nakamura F, Musha T, Kobayashi Y. Association between novel arterial stiffness indices and risk factors of cardiovascular disease. BMC Cardiovasc Disord 2016; 16:211. |
| [63] | Naqvi TZ, Lee MS. Carotid intima-media thickness and plaque in cardiovascular risk assessment. JACC Cardiovasc Imaging 2014; 7:1025-1038. |
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