Sonographic Assessment of Uterine and Ovarian Development in Normal Girls aged 2-18 Years in Pakistan

doi:10.26599/AUDT.2025.240008

Advanced Ultrasound in Diagnosis and Therapy ›› 2025, Vol. 9 ›› Issue (3): 277-282.doi: 10.26599/AUDT.2025.240008

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Sonographic Assessment of Uterine and Ovarian Development in Normal Girls aged 2-18 Years in Pakistan

Irshad Ayesha^a, Muhammad Yousaf Farooq Syed^b^,^c^,^*(), Fatima Mehreen^a, Gilani Syed Amir^c^,^d, Yousaf Muhammad^a

^aUniversity Institute of Radiological Sciences & Medical Imaging Technology, Faculty of Allied Health Sciences, The University of Lahore
^bRadiography and Imaging Technology, Green International University, Lahore, Pakistan
^cOffice of Research, Innovation and Commercialization, Green International University, Lahore. Pakistan
^dDepartment of Medical Diagnostic imaging, College of Health Sciences, University of Sharjah, United Arab Emirates

Received:2024-12-15 Revised:2025-02-14 Accepted:2025-03-04 Online:2025-09-30 Published:2025-10-13
Contact: Radiography and Imaging Technology, Green International University, Lahore, Pakistan. Office of Research, Innovation and Commercialization, Green International University, Lahore, Pakistan. e-mail:yousafgelani@gmail.com(SMY F),

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Abstract

Abstract:

Objective Uterine and ovarian development is influenced by both age and hormonal milieu. Sonographic assessment of normal pubertal and pre-puberty girls provides critical insights into the physiological trajectory of female gonadal maturation and its potential pathological deviations.
Methods This was a cross-sectional study conducted at Gilani Ultrasound Center, Lahore, Pakistan. The duration of the study was 9 months. Uterus length, width, height, volume, right/left ovary volume and Fundo/Cervical ratio were measured.
Results A total of 384 subjects were included in our study, categorizing them into pre-puberty (age 2-6 years), early puberty (age 7-11 years), and late puberty (age 12-18 years) groups. In the pre-puberty group (n = 111, mean age 4.29 ± 1.20 years), uterine measurements revealed a mean length of 2.95 cm, height of 0.97 cm, width of 1.41 cm, and volume of 4.82 cm³. The mean volumes of the right and left ovaries were 1.24 cm³ and 1.10 cm³, respectively, with a mean F/C ratio of 1.33. For the early puberty group (n = 99, mean age 9.15 ± 1.45 years), uterine measurements included a mean length of 4.03 cm, height of 1.22 cm, width of 1.80 cm, and volume of 12.37 cm³. In the late puberty group (n = 31, mean age 12.63 ± 1.21 years), uterine measurements showed a mean length of 5.29 cm, height of 1.82 cm, width of 2.65 cm, and volume of 31.11 cm³. The mean volumes of the right and left ovaries were 4.70 cm³ and 5.26 cm³, respectively, with a mean F/C ratio of 1.26.
Conclusion Uterine and ovarian dimensions, including volumes, correlate directly with age and pubertal status, except for the (Fundus/Cervical) ratio, which shows individual variability. This normative data could serve as a basis for the evaluation of Uterine and ovarian dimensions and volume in the local population.

Key words: Normotensive; Uterus volume; Ovarian volume; Puberty

Irshad Ayesha, Muhammad Yousaf Farooq Syed, Fatima Mehreen, Gilani Syed Amir, Yousaf Muhammad. Sonographic Assessment of Uterine and Ovarian Development in Normal Girls aged 2-18 Years in Pakistan. Advanced Ultrasound in Diagnosis and Therapy, 2025, 9(3): 277-282.

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References 18

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Variables	Pre-puberty			Puberty
Variables	2-6 years	7-11 years	12-18 years	7-11 years	12-18 years
n	111	99	31	8	135
Age (years)	4.29 ± 1.20	9.15 ± 1.45	12.63 ± 1.21	9.50 ± 1.31	15.21 ± 2.01
Uterus length (cm)	2.95 ± 0.66	4.03 ± 1.09	5.29 ± 1.22	4.96 ± 1.65	7.18 ± 0.92
Uterus height (cm)	0.97 ± 0.50	1.22 ± 0.62	1.82 ± 0.68	1.75 ± 0.86	2.99 ± 0.56
Uterus width (cm)	1.41 ± 0.53	1.80 ± 0.70	2.65 ± 0.74	2.58 ± 1.04	3.81 ± 0.79
Uterus volume (cm³)	4.82 ± 5.20	12.37 ± 15.54	31.11 ± 28.02	31.52 ± 31.82	86.16 ± 38.75
Right ovary volume (cm³)	1.24 ± 0.83	3.13 ± 2.06	4.70 ± 2.62	3.33 ± 1.50	6.64 ± 2.67
Left ovary volume (cm³)	1.10 ± 0.68	2.68 ± 1.74	5.26 ± 3.59	3.10 ± 1.42	6.83 ± 2.68
F/C ratio	1.33 ± 0.42	1.26 ± 0.29	1.26 ± 0.29	1.34 ± 0.41	1.47 ± 0.34

Items		Total (n)	Pre-puberty (n)	Puberty (n)
Uterus volume (cm³)	0-50	265	233	32
	50-100	75	8	67
	101-150	33	0	33
	151-200	10	0	10
	201-250	1	0	1
Uterus height (cm)	0.1-1.0	132	130	2
	1.1-2.0	99	93	6
	2.1-3.0	97	16	81
	3.1-4.0	51	2	49
	4.1-5.0	5	0	5
Uterus width (cm)	0.1-1.0	37	37	0
	1.1-2.0	143	138	5
	2.1-3.0	82	55	27
	3.1-4.0	62	10	52
	4.1-5.0	53	1	52
	5.1-6.0	7	0	7
Uterus length (cm)	0.1-2.0	12	12	0
	2.1-4.0	160	158	2
	4.1-6.0	73	59	14
	6.1-8.0	114	12	102
	8.1-10.0	25	0	25
Right ovary volume (cm³)	0-5.0	275	221	54
	5.1-10.0	91	20	71
	10.1-15.0	18	0	18
Left ovary volume (cm³)	0-5.0	269	219	50
	5.1-10.0	93	19	74
	10.1-15.0	22	3	19
F/C ratio	0.1-1.0	45	39	6
	1.1-2.0	328	198	130
	2.1-3.0	11	4	7
Total		384	241	143

Model Summary
Model	R	R Square	Adjusted R Square	P value
1	0.849 ^a	0.720	0.719	< 0.001

Sonographic Assessment of Uterine and Ovarian Development in Normal Girls aged 2-18 Years in Pakistan

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