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Advanced Ultrasound in Diagnosis and Therapy ›› 2025, Vol. 9 ›› Issue (3): 277-282.doi: 10.26599/AUDT.2025.240008

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  • 收稿日期:2024-12-15 修回日期:2025-02-14 接受日期:2025-03-04 出版日期:2025-09-30 发布日期:2025-10-13

Sonographic Assessment of Uterine and Ovarian Development in Normal Girls aged 2-18 Years in Pakistan

Irshad Ayeshaa, Muhammad Yousaf Farooq Syedb,c,*(), Fatima Mehreena, Gilani Syed Amirc,d, Yousaf Muhammada   

  1. aUniversity Institute of Radiological Sciences & Medical Imaging Technology, Faculty of Allied Health Sciences, The University of Lahore
    bRadiography and Imaging Technology, Green International University, Lahore, Pakistan
    cOffice of Research, Innovation and Commercialization, Green International University, Lahore. Pakistan
    dDepartment of Medical Diagnostic imaging, College of Health Sciences, University of Sharjah, United Arab Emirates
  • Received:2024-12-15 Revised:2025-02-14 Accepted:2025-03-04 Online:2025-09-30 Published:2025-10-13
  • Contact: Radiography and Imaging Technology, Green International University, Lahore, Pakistan. Office of Research, Innovation and Commercialization, Green International University, Lahore, Pakistan. e-mail:yousafgelani@gmail.com(SMY F)

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Abstract:

Objective Uterine and ovarian development is influenced by both age and hormonal milieu. Sonographic assessment of normal pubertal and pre-puberty girls provides critical insights into the physiological trajectory of female gonadal maturation and its potential pathological deviations.
Methods This was a cross-sectional study conducted at Gilani Ultrasound Center, Lahore, Pakistan. The duration of the study was 9 months. Uterus length, width, height, volume, right/left ovary volume and Fundo/Cervical ratio were measured.
Results A total of 384 subjects were included in our study, categorizing them into pre-puberty (age 2-6 years), early puberty (age 7-11 years), and late puberty (age 12-18 years) groups. In the pre-puberty group (n = 111, mean age 4.29 ± 1.20 years), uterine measurements revealed a mean length of 2.95 cm, height of 0.97 cm, width of 1.41 cm, and volume of 4.82 cm3. The mean volumes of the right and left ovaries were 1.24 cm3 and 1.10 cm3, respectively, with a mean F/C ratio of 1.33. For the early puberty group (n = 99, mean age 9.15 ± 1.45 years), uterine measurements included a mean length of 4.03 cm, height of 1.22 cm, width of 1.80 cm, and volume of 12.37 cm3. In the late puberty group (n = 31, mean age 12.63 ± 1.21 years), uterine measurements showed a mean length of 5.29 cm, height of 1.82 cm, width of 2.65 cm, and volume of 31.11 cm3. The mean volumes of the right and left ovaries were 4.70 cm3 and 5.26 cm3, respectively, with a mean F/C ratio of 1.26.
Conclusion Uterine and ovarian dimensions, including volumes, correlate directly with age and pubertal status, except for the (Fundus/Cervical) ratio, which shows individual variability. This normative data could serve as a basis for the evaluation of Uterine and ovarian dimensions and volume in the local population.

Key words: Normotensive, Uterus volume, Ovarian volume, Puberty

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VariablesPre-pubertyPuberty
2-6 years7-11 years12-18 years7-11 years12-18 years
n11199318135
Age (years)4.29 ± 1.209.15 ± 1.4512.63 ± 1.219.50 ± 1.3115.21 ± 2.01
Uterus length (cm)2.95 ± 0.664.03 ± 1.095.29 ± 1.224.96 ± 1.657.18 ± 0.92
Uterus height (cm)0.97 ± 0.501.22 ± 0.621.82 ± 0.681.75 ± 0.862.99 ± 0.56
Uterus width (cm)1.41 ± 0.531.80 ± 0.702.65 ± 0.742.58 ± 1.043.81 ± 0.79
Uterus volume (cm3)4.82 ± 5.2012.37 ± 15.5431.11 ± 28.0231.52 ± 31.8286.16 ± 38.75
Right ovary volume (cm3)1.24 ± 0.833.13 ± 2.064.70 ± 2.623.33 ± 1.506.64 ± 2.67
Left ovary volume (cm3)1.10 ± 0.682.68 ± 1.745.26 ± 3.593.10 ± 1.426.83 ± 2.68
F/C ratio1.33 ± 0.421.26 ± 0.291.26 ± 0.291.34 ± 0.411.47 ± 0.34

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ItemsTotal (n)Pre-puberty (n)Puberty (n)
Uterus volume (cm3)0-5026523332
50-10075867
101-15033033
151-20010010
201-250101
Uterus height (cm)0.1-1.01321302
1.1-2.099936
2.1-3.0971681
3.1-4.051249
4.1-5.0505
Uterus width (cm)0.1-1.037370
1.1-2.01431385
2.1-3.0825527
3.1-4.0621052
4.1-5.053152
5.1-6.0707
Uterus length (cm)0.1-2.012120
2.1-4.01601582
4.1-6.0735914
6.1-8.011412102
8.1-10.025025
Right ovary volume
(cm3)		0-5.027522154
5.1-10.0912071
10.1-15.018018
Left ovary volume
(cm3)		0-5.026921950
5.1-10.0931974
10.1-15.022319
F/C ratio0.1-1.045396
1.1-2.0328198130
2.1-3.01147
Total384241143

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Model Summary
ModelRR SquareAdjusted R SquareP value
10.849 a0.7200.719< 0.001

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