ADVANCED ULTRASOUND IN DIAGNOSIS AND THERAPY >
Sonographic Assessment of Uterine and Ovarian Development in Normal Girls aged 2-18 Years in Pakistan
Received date: 2024-12-15
Revised date: 2025-02-14
Accepted date: 2025-03-04
Online published: 2025-10-13
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Objective Uterine and ovarian development is influenced by both age and hormonal milieu. Sonographic assessment of normal pubertal and pre-puberty girls provides critical insights into the physiological trajectory of female gonadal maturation and its potential pathological deviations.
Methods This was a cross-sectional study conducted at Gilani Ultrasound Center, Lahore, Pakistan. The duration of the study was 9 months. Uterus length, width, height, volume, right/left ovary volume and Fundo/Cervical ratio were measured.
Results A total of 384 subjects were included in our study, categorizing them into pre-puberty (age 2-6 years), early puberty (age 7-11 years), and late puberty (age 12-18 years) groups. In the pre-puberty group (n = 111, mean age 4.29 ± 1.20 years), uterine measurements revealed a mean length of 2.95 cm, height of 0.97 cm, width of 1.41 cm, and volume of 4.82 cm3. The mean volumes of the right and left ovaries were 1.24 cm3 and 1.10 cm3, respectively, with a mean F/C ratio of 1.33. For the early puberty group (n = 99, mean age 9.15 ± 1.45 years), uterine measurements included a mean length of 4.03 cm, height of 1.22 cm, width of 1.80 cm, and volume of 12.37 cm3. In the late puberty group (n = 31, mean age 12.63 ± 1.21 years), uterine measurements showed a mean length of 5.29 cm, height of 1.82 cm, width of 2.65 cm, and volume of 31.11 cm3. The mean volumes of the right and left ovaries were 4.70 cm3 and 5.26 cm3, respectively, with a mean F/C ratio of 1.26.
Conclusion Uterine and ovarian dimensions, including volumes, correlate directly with age and pubertal status, except for the (Fundus/Cervical) ratio, which shows individual variability. This normative data could serve as a basis for the evaluation of Uterine and ovarian dimensions and volume in the local population.
Key words: Normotensive; Uterus volume; Ovarian volume; Puberty
Irshad Ayesha , Muhammad Yousaf Farooq Syed , Fatima Mehreen , Gilani Syed Amir , Yousaf Muhammad . Sonographic Assessment of Uterine and Ovarian Development in Normal Girls aged 2-18 Years in Pakistan[J]. ADVANCED ULTRASOUND IN DIAGNOSIS AND THERAPY, 2025 , 9(3) : 277 -282 . DOI: 10.26599/AUDT.2025.240008
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