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Advanced Ultrasound in Diagnosis and Therapy ›› 2023, Vol. 7 ›› Issue (4): 412-415.doi: 10.37015/AUDT.2023.220027

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  • 收稿日期:2022-07-24 修回日期:2022-10-02 接受日期:2022-10-05 出版日期:2023-12-30 发布日期:2023-10-23

The Value of CEUS in the Diagnosis and Treatment of Thyroid Primary Squamous Cell Carcinoma: A Case Report

Yiming Li, BMa, Jing Xiao, MDa, Fang Xie, MDa, Yu Lin, BMb, Mingbo Zhang, MDa,*(), Yukun Luo, MDa,*()   

  1. aDepartment of Ultrasound, the First Medical Center of PLA General Hospital, Beijing, China
    bDepartment of pathology, the First Medical Center of PLA General Hospital, Beijing, China
  • Received:2022-07-24 Revised:2022-10-02 Accepted:2022-10-05 Online:2023-12-30 Published:2023-10-23
  • Contact: Department of Ultrasound, the First Medical Center of PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, China. e-mail: owsifanduizhe@126.com; lyk301@163.com

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Abstract:

Primary squamous cell carcinoma of the thyroid (PSCCT) is a rare clinical disease characterized by rapid growth, high invasiveness, and a poor prognosis. A 66-year-old male patient was admitted due to throat pain and dysphagia. Ultrasound revealed a calcified hypoechoic mass in the right lobe of the thyroid gland, measuring approximately 35.3 ml. Ultrasound and PET-CT both indicated high suspicion of malignancy. The patient underwent contrast-enhanced US-guided biopsy, and the pathological results revealed poorly differentiated squamous cell carcinoma. CEUS was performed regularly during the Chemotherapy combined with pembrolizumab (PD-1) treatment courses. The vital area was significantly reduced with neither recurrence nor cervical lymph node metastasis. Surgical resection and chemotherapy combined with immunotherapy had a significant treatment effect in this case. CEUS is helpful for diagnosis confirmation, biopsy guidance and efficacy evaluation and has important clinical application value.

Key words: Ultrasonography, Image enhancement, Thyroid gland, Squamous cell carcinoma, Biopsy

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