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Advanced Ultrasound in Diagnosis and Therapy ›› 2023, Vol. 7 ›› Issue (4): 405-408.doi: 10.37015/AUDT.2023.220049

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  • 收稿日期:2022-12-22 修回日期:2023-03-09 接受日期:2023-05-09 出版日期:2023-12-30 发布日期:2023-10-23

An Epstein-Barr Virus Positive Lymphoepithelioma-Like Cholangiocarcinoma in A Young Woman with Chronic Hepatitis B Treated through Microwave Ablation: A Case Report and Literature Review

Lanxia Zhang, MMa, Qingjing Zeng, MDa, Guanghui Guo, MMa, Xuqi He, MMa, Kai Li, MDa,*()   

  1. aDepartment of Ultrasound, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
  • Received:2022-12-22 Revised:2023-03-09 Accepted:2023-05-09 Online:2023-12-30 Published:2023-10-23
  • Contact: Kai Li, MD E-mail:likai@mail.sysu.edu.cn

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Abstract:

Lymphoepithelioma-like cholangiocarcinoma (LELCC) is a rare subtype of carcinoma that is poorly reported. We report a case of LELCC in a 28-year-old female with chronic hepatitis B. She underwent secondary microwave ablation for residual tumor following the failure of radiofrequency ablation (RFA). Image fusion technology was used to accurately diagnose that the second lesion represented residual tumor. This case is the second successful application of microwave ablation in the treatment of LELCC. We first reviewed the ultrasonographic features of LELCC. We report this case to improve our understanding of this disease and provide evidence for its clinical treatment.

Key words: Lymphoepithelioma-like cholangiocarcinoma, Microwave ablation, Ultrasound

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Reference Age Sex EBV HBV HCV Size (cm) Ultrasound CEUS
1 Our 28 F P P N 1.2 Hypoechoic lesion with no obvious blood flow signals Hyperenhancement in the arterial phase, hypoenhancement in the portal phase and delayed phase
2 Chen et al. [14] 67 F P N P 5 Mixed echoic Unknown
3 Chen et al. [14] 41 M N P N 3 Hypoechoic Unknown
4 Jeng et al. [15] 50 F P P N 4 Hypoechoic Unknown
5 Liao et al. [2] 35 F P P N 1.7 Hypoechoic Unknown
6 Liang et al. [16] 64 M P P N 2.3 Hypoechoic nodule with no blood flow signals Unknown
7 Liang et al. [16] 40 M P P N 3.5 Hypoechoic nodule with no blood flow signals Hyperenhancement in the arterial phase, hypoenhancement and rim-like slight hyperenhancement in the portal phase and delayed phase
8 Nogami et al. [5] 27 F P P N 1 Hypoechoic Hyperenhancement in the arterial phase, perfusion defect in the Kupffer phase
9 Zhang et al. [17] 36 F P N N 11.5 Hypoechoic Unknown
10 Li et al. [6] 51 M N N P 5.1 Hypoechoic Hyperenhancement in the arterial phase, hypoenhancement in the portal and delay phases
11 Chen et al. [18] 74 F P N N 4.3 Hypoechoic and aberrant subcapsular vascular patterns Enhancement in the arterial phase, hypoenhancement in the portal and delay phases
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